Categories: Drugs

Side effects of prednisone

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Discover the side effects of prednisone.

Corticosteroid with great anti-inflammatory power.

Family: Corticosteroids

What is it taken for?

Prednisone is a medication that belongs to the group of corticosteroids or corticosteroids, which are hormones produced by our body.

Prednisone is used to treat symptoms caused by a sudden drop in corticosteroid levels in the body, such as in Addison’s disease, and it also has great anti-inflammatory power. Side effects of prednisoneSide effects of prednisone

Corticosteroids reduce the release of substances that cause inflammation produced by some cells of the body in response to certain stimuli, for example, allergic or immune. Thus, prednisone will be useful in diseases characterized by excessive inflammation.

The therapeutic indications of prednisone are the following:

•Replacement therapy in Addison’s disease and adrenogenital syndrome.

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•Articular and muscular acute and chronic rheumatic processes.

•Bronchial asthma, pulmonary fibrosis, status asthmaticus.

•Severe acute urticaria, Quincke’s edema, Lyell’s syndrome, severe drug rash, severe inflammatory dermatosis, large-area dermatitis, lichen Drusus exanthemata, erythroderma, Sweet’s syndrome, granulomatous skin diseases, post-zoster neuralgia, Jarisch-Herxheimer reaction in the treatment of syphilis with penicillin, cavernous hemangioma, Behçet’s disease, pyoderma gangrenosum, pemphigus.

•Autoimmune hemolytic anemia, thrombocytopenic purpura, thrombocytopenia, acute lymphoblastic leukemia, Hodgkin’s disease, non-Hodgkin’s lymphomas, chronic lymphatic leukemia, Waldenström’s disease, multiple myeloma, agranulocytosis, palliative treatment of malignant diseases, organ transplants.

•Ulcerative colitis, hepatitis.

•Glomerulonephritis, idiopathic retroperitoneal fibrosis, nephrotic syndrome.

•Allergic conjunctivitis, keratitis, iritis, iridocyclitis, chorioretinitis.

Side effects of prednisone

•Gastric and duodenal ulcers, reduced glucose tolerance, and lower resistance to infection.

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•In long-term treatments: Cushing’s syndrome, faciotroncular obesity with full moon face, amenorrhea, hirsutism, impotence.

•Steroid acne, delayed wound healing, stretch marks.

•Muscle atrophy and weakness, osteoporosis.

•Glaucoma, cataracts.

•Depression, irritability, euphoria, increased appetite, and vigor, pseudotumor cerebri, manifestations of latent epilepsy.

•Gastric and duodenal ulcers, gastrointestinal bleeding.

•Diabetes mellitus, electrolyte disturbances, inactivity or atrophy of the adrenal cortex, growth retardation in children.

•high blood pressure

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•Lymphopenia, eosinopenia, polycythemia, worsening of immune processes, masking of infections.

When should it not be used?

•In case of hypersensitivity to prednisone.

•In long-term treatments are absolute contraindication: acute viral infections.

•Period between eight weeks before and two weeks after a prophylactic vaccination.

•Relative contraindications are considered if, together with the steroid treatment, there is another disease that can be activated or worsened due to this treatment.

These contraindications are not considered if the second disease can be compensated by specific treatment: peptic ulcer, bacterial infection, systemic mycosis, arterial hypertension, diabetes mellitus, osteoporosis, psychiatric history, osteomalacia, glaucoma.

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